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Antihypertensive Drugs Pharmacology!

By- PharmaEdu

Pharmaeducation.in

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ACE inhibitors

ACE inhibitors are among the most widely prescribed cardiovascular medicines.

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Angiotensin II receptor antagonists

Examples: Candesartan,  Irbesartan, Losartan,Telmisartan

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Diuretics eliminate excess sodium and water from the body. Some diuretic classes also eliminate potassium, increasing the risk of hypokalemia.

Diuretics

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There are two classes of calcium channel blockers: – 1.dihydropyridine  2.non-dihydropyridine.

Calcium channel blockers

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Beta-blockers

Beta-blockers are not first-line agents in the treatment of hypertension. However, they may be used in cases of treatment-resistant hypertension or as an add-on treatment option.

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used to treat hypertension in treatment-resistant cases where other drugs have proven insufficient.

Alpha-blockers

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Alpha-2 agonists are typically prescribed alongside a diuretic drug.

Alpha-2 agonists

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Renin Inhibitors

Renin inhibitors are, then, an effective way to block the effects of angiotensin II and reduce blood pressure.

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Vasodilators

Sodium nitroprusside has been used in cases of hypertensive emergencies. It is administered via the intravenous route and so has a rapid onset of effect.

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